As you've noticed, weight loss on T3 therapy can sometimes be difficult to predict. It's as if, at times, factors and variables line up in such a way that the weight begins to drop off. And at other times, it seems to slow inexplicably. It can also sometimes be difficult to get the weight loss to resume when it stops.

I've often told patients that if they find themselves losing weight then they should do everything they can to "not rock the boat" (by missing doses or by cycling to try to get a greater effect) and to let as much of the weight come off as possible.

One benefit to getting weight off while the getting is good is that the more weight people are able to get off, it is often easier for them to continue losing (this is true when patients are using T3 therapy to keep their temperatures up, while the opposite is true when people are dieting unprotected).

But to answer your questions, I think that people can begin watching their diet and exercise when their temperature is normal (even if you are cycling up and not yet captured) but I would suggest avoiding extremes if they are making it difficult to manage the T3 therapy and keep it stabilized.

When weight loss has stopped for a period of weeks, perhaps another cycle might prove helpful in getting it started again. However, I have seen people have difficulty getting their weight loss started again, even with cycling. Sometimes, they might start losing weight while they're weaning off. And if they do, they might want to stay at that dose and lose as much as they can. It's hard to predict what factors line up to result in weight loss, that's why I think it prudent to take careful advantage of it whenever it occurs in the cycling process.

Hope that helps,
Denis Wilson, MD  

I have not noticed whether wide-ranging temperatures before treatment are predictive for increased chances of unsteadiness during treatment with T3. It's possible that the wide-ranging temperatures are due to some other factor other than just T3. It's hard for me to imagine unsteady endogenous T3 supplies though we must suppose that is possible.

One thing to bear in mind is that T3 therapy begins suppressing endogenous T3 immediately. The concern with unsteady T3 levels grows with the dosage of T3 people are taking. The higher the dose of T3, the lower the endogenous (made by the body) production. Thus, it seems that how well a person tolerates exogenous T3 (taken by mouth) may be more important than how steady their own T3 supply. And the only way to determine that is by trying the treatment to see.

Nevertheless, it does make sense that T3 unsteadiness from any source might be unfavorable so I feel it's a good consideration.

You might also consider supporting the adrenal system. The adrenal system often has to work overtime trying to make up for shortcomings in the thyroid system.

Best wishes,
D. Wilson, MD  

Yes, it is possible to go between Hypo and Hyper active thyroid and I can imagine how that could lead to symptoms reminiscent of Bipolar illness.

I recommend that you introduce your Naturopathic Dr. to ThyroCalm Px. It is superb for overactive thyroid, and also has components that are often used in underactive thyroid. Our supplements are designed to stabilize the function of the thyroid system and to nourish and strengthen the health of the thyroid system.

Best regards,
Denis Wilson, MD